Rawashdeh A, Alnawaiseh N. The Effect of Loftier-Intensity Aerobic Practise on the Pulmonary Function Among Inactive Male Individuals. Biomed Pharmacol J 2018;eleven(two).

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Manuscript accepted on :04 May 2018
Published online on: eleven-05-2018

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Arwa Rawashdehi and Nedal Alnawaiseh2

1Departement of Physiology and Pathology, Faculty of Medicine, Mutah Academy, Hashemite kingdom of jordan.

2Departement of Public Wellness, Faculty of Medicine, Mutah University, Hashemite kingdom of jordan.

Corresponding Author E-mail: rawashdeha@yahoo.com

DOI : https://dx.doi.org/10.13005/bpj/1427

Abstract

A spirometer is an of import instrument in the assessment of the lung functions. FVC, FEV1, MVV and ratio of FEV1/FVC are indicators of stiff respiratory function that deteriorate due to a sedentary lifestyle. Prolonged aerobic exercises are thought to amend aerobic chapters and to accept a favorable consequence on lung office. Thus, the main aim of this written report was to investigate the effect of such aerobic exercise for 3 weeks, specifically continuous treadmill running, on lung office (FVC, FEV1, ratio of FEV1/FVC, and MVV) in inactive yet healthy male individuals. For this study, 72 inactive male individuals were given a pulmonary function test. The exam was performed 3 times for each session (starting with 5 minutes and increasing past ten minutes every iii sessions, up to a maximum of 25 minutes), and its hateful value was used for assay. Practice was performed three days a week for three weeks. The Wilcoxon test was done to determine changes pre- to post-test. Repeated-measure analyses were used to compare the changes of pulmonary values betwixt high-intensity sessions. Spearman correlation rho was conducted to assess association between MVV, FVC, and FEV1, and the Friedman examination was used to compare the mean ratio of FEV1/FVC before and after do of different intensities. FEV1, MVV and a ratio of FEV1/FVC were significantly improved after high-intensity aerobic practice of different intensities. In add-on positive relation of MVV with FEV1 improvements was found. In contrast, there were insignificant improvements in FVC earlier and after exercise of unlike intensities and with no positive relation of MVV improvements. The improvements in MVV could reverberate subtle changes in lung function or airway reactivity not detected by the FVC test. In addition, college exercise intensity or longer elapsing may be needed to affect other lung function parameters like MVV, FEV1 and FEV1/FVC. Thus our results demonstrate that high-intensity aerobic do on the treadmill has a positive effect on the pulmonary part of inactive healthy subjects.

Keywords

FVC; FEV1; MVV  High-Intensity Aerobic Exercise; Pulmonary Office;

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Rawashdeh A, Alnawaiseh N. The Consequence of Loftier-Intensity Aerobic Practise on the Pulmonary Function Among Inactive Male Individuals. Biomed Pharmacol J 2018;11(2). Available from: http://biomedpharmajournal.org/?p=20400

Introduction

Exercise is a reliable method of testing the physical abilities and physiological reactions that class the basis of expert health and well-being and can be used, for example, to measure the ability to endure stress and carry on in circumstances where an unhealthy person cannot. At the same time, lung function is a vital predictive tool of both morbidity and bloodshed in medical exercise. Many studies have shown that respiratory indices such equally forced vital chapters (FVC), forced expiratory volume in 1 2nd (FEV1), and maximum voluntary ventilation (MVV) are potent indicators of lung function, as they refuse noticeably due to sedentary lifestyle.ane-3

In one study, 6790 subjects were followed for xix months. Those with agile lifestyles showed an improvement of fifty ml in FEV1 and lxx ml in FVC; notwithstanding, subjects with sedentary lifestyles experienced a xxx ml reduction in FEV1 and xx ml reduction in FVC.fourMoreover, other studies have shown that physical action tin improve lung role dramatically in subjects with diseases like asthma and in children with intellectual disabilities.five-half-dozenThese findings suggest that a sedentary lifestyle tin can cause the deterioration of respiratory indices and might put one at high risk for developing chronic obstructive pulmonary disease. Appropriate interventions such equally physical activity programs, however, may prevent such deterioration.

Other recent studies accept investigated the effect of exercise on pulmonary function. For example, dancing,seven playing gate ball,8 and exercising core muscles,ix were reported to have had a positive effect on pulmonary role in the elderly. The results of such studies take led to increasing involvement in practise programs that can improve pulmonary function and forestall respiratory disease. although there have been many studies that bear witness aerobic exercises extensively improves the endurance and force of respiratory muscles, decrease resistance and increment lung elasticity and alveolar expansion by promoting the expansion of pulmonary volumes and capacities, others have institute that information technology has no pregnant effect.x

A spirometer is an important in the cess of the lung functions.FVC; FEV1, MVV and ratio of FEV1/FVC are indicators of strong respiratory role that deteriorate due to a sedentary lifestyle.

Prolonged aerobic exercises are idea to improve aerobic chapters and to have a favorable effect on lung role. Thus, the primary aim of this study was to investigate the effect of such aerobic exercise for three weeks, specifically continuous treadmill running, on lung function (FVC, FEV1, ratio of FEV1/FVC, and MVV) in inactive yet healthy male individuals.

Mehods

Sample Size

For this study, 72 male subjects were recruited.

Report Population

Subjects (aged 18–50 years) were recruited. Informed consent was taken from each afterward they had been given a detailed explanation of the experiment. The subjects were asked to complete questionnaires on medical history to ensure they are in a good wellness (no astute illnesses related to respiratory or heart disease)

Sampling Method and Study Design

Pre-test/mail service-test studies measure the change in a state of affairs. They are oft used to measure the efficacy of an intervention and can be considered comparative cantankerous-sectional. For this study, 72 male subjects were randomly selected by simple random sampling technique (SRS).

Sources and Methods of Data Drove

Measurements of respiratory indices were taken iii times in the pre- and post-practice phases of each session, and their mean values were used for analysis. Subjects were asked not to change their habitual physical activity during the study and not to take whatsoever nutritional supplements.

Inclusion Criteria

Subjects recruited for this study had to come across the criteria listed below:

Age 18 or older

In skillful health (no acute illnesses related to respiratory or heart illness)

Cooperative

Protocol

The high-intensity exercise training program consisted of continuous treadmill running (grade = 0%) three days a week for three weeks. Each session began with a warmup period of five minutes. For the session itself, running time started at v minutes, and this interval was increased past ten minutes every three sessions, upward to a maximum of 25 minutes. The speed of running was adapted according to the target heartrate zone (75–85% HR max).

Measurements

Pulmonary function tests were carried out by SPIROVIT SP-1 spirometer to decide FVC, FEV1, FEV1/FVC, and MVV. Subjects had to remain in the direct sitting or standing position throughout the test, and a olfactory organ clip was tightly attached to the nostrils, allowing no air to escape during the test. A mouthpiece was placed at least two centimeters into the discipline's rima oris, with lips airtight around it.

FVC Maneuver: Each subject area was asked to inhale completely and rapidly, pausing less than one 2d at total lung capacity (TLC), and then exhale as quickly and completely every bit possible, expelling all the air. Forced vital chapters (FVC), forced expiratory book in the first second (FEV1), and forced expiratory volume in the offset second/forced vital capacity (FEV1/FVC) were obtained and recorded by the apparatus.

MVV maneuver: Subjects were tested in the sitting position while wearing a nose prune. They were instructed to breathe as rapidly and deeply equally possible for 12 seconds after obtaining at to the lowest degree three resting tidal breaths with an airtight seal around the mouthpiece.

Statistical Analysis

The values are reported as mean ± standard deviations. Statistical analysis was conducted using SPSS software version 16. The Wilcoxon exam, a nonparametric analysis (paired t-examination), was done to make up one's mind changes pre- to post-test. Repeated-measure analyses were used to compare the changes of pulmonary values between high-intensity sessions. Spearman correlation rho was conducted to assess association between MVV, FVC, and FEV1, and the Friedman test was used to compare the mean ratio of FEV1/FVC before and after practise of unlike intensities.

Results

Table 1 shows the mean of the anthropometric characteristics of the 72 subjects. The mean age was 30.94 ± 11.29 years, the mean elevation was 172.65 ± 5.72 cm, and the mean weight was 79.67 ± 12.56 kg.

Table 1: Anthropometric characteristics (one thousand ± SD) of total subjects

Age(twelvemonth) Height(cm) Weight(kg)
Mean xxx.94 172.65 79.67
Std. Deviation (SD) xi.29 5.72 12.56

Table 2 shows the baseline spirometry information of predicted values for the 72 subjects. The mean predicted FVC was iv.00 ± 0.51 L, mean predicted FEV1 was iii.76 ± 0.55 L, and mean predicted MVV was 127.14 ± 22.44 L.

Tabular array two: Baseline spirometric data (m ± SD) of predicted values

pred FVC (50) pred FEV1 (Fifty) pred MVV (50)
Mean 4.00 iii.76 127.14
Std. Departure 0.51 0.55 22.44

Table 3(A) shows the baseline spirometry information of FVC and FEV1 pre- and mail-exercise at dissimilar intensities. The hateful pre-exercise FVC was 3.eighty ± 0.71 50, and the mean pre-practice FEV1 was 3.37 ± 0.77 L. Mail service-practise mean FVC after 5, 15, and 25 minutes was three.92 ± 0.56 50, 3.92 ± 0.70 L, and 3.96 ± 0.48 L respectively. The post-practice mean FEVone after 5, 15, and 25 minutes was 3.73 ± 0.62 L, 3.86 ± 0.49 50, and three.93 ± 0.53 L respectively (the trend hither is obvious).

Tabular array 3(A): Baseline spirometric information (m ± SD) of FVC and FEV1 before and later on do at different intensities

Pre exercise FVC 5 min post exercise  FVC 15min mail service exercise  FVC 25 min postal service exercise  FVC Pre exercise FEVane 5 min post exercise  FEV1 15 min post practice  FEVane 25 min postal service exercise  FEV1
Mean 3.fourscore 3.92 iii.92 iii.96 3.37 3.73 3.86 3.93
SD 0.71 0.56 0.lxx 0.48 0.77 0.62 0.49 0.53

Tabular array three(B) shows the baseline spirometry information of MVV before and after exercise at different intensities. The pre-exercise hateful MVV was 125.47 ± 32.97 50, the mail service-exercise mean MVV later five, 15, and 25 minutes was 134.26 ± 30.21 L, 135.54 ± 53.18 L, and 143.95 ± 31.34 Fifty respectively, and the post-exercise means of FVC, FEVane, and MVV for all intensities were 3.94 ± 0.30 L, 3.84 ± 0.34 Fifty, and 137.92 ± 21.53 L respectively. The improvement here is obvious when compared to pre-hateful values for all lung functions (FVC, FEV1, and MVV).

Tabular array 3(B): Baseline spirometric data (g ± SD) of MVV earlier and after do at different intensities

Pre exercise MVV v min post exercise MVV 15 min postal service exercise  MVV 25min post exercise  MVV FVC-Postal service exercise FEV1-post exercise MVV- post exercise
Mean 125.47 134.26 135.54 143.95 three.94 3.84 137.92
SD 32.97 thirty.21 53.eighteen 31.34 0.thirty 0.34 21.53

The FEV1/FVC ratios earlier and after practise at different intensities were measured past the Friedman test, which showed that the pre-exercise FEV1/FVC ratio is significantly lower than the post-exercise mean of the FEV1/FVC ratio with p-value < 0.001.

Tabular array 4 shows the paired t-test. The means of pre-exercise FEVane and MVV were significantly lower than the mail service-exercise means, with p < 0.001 and p = 0.003, respectively. However, the mean of FVC showed no significant difference before or afterward practise, with p = 0.241.

Tabular array 4: Lung function indices before and afterward practise (paired t-exam)

Variable Pre exercise Postal service exercise P-Value
FVC(L) 3.80±0.71 3.94±0.30 0.241
FEV1 (L) iii.37±0.77 3.84±0.34 <0.001*
MVV(L) 125.47±32.97 137.92±21.53 0.003*

*Significantly different before and afterwards practise (p < 0.05). FVC: forced expiratory volume. FEV1: forced expiratory volume in i second. MVV: maximum voluntary ventilation.

Post-practice ways at different intensities of FEV1 and MVV were significantly higher than pre-mean values, with p < 0.001 and 0.039 respectively. However, FVC showed no significant difference betwixt pre- and post-exercise means at different intensities (p = 0.444) (Table v).

Table five: ANOVA of lung function before and afterwards exercise at different intensities

Variable Pre exercise Post do 5min Post exercise 15min Post exercise 25min F-test P-Value
FVC(L) 3.80 3.92 3.93 3.96 0.895 0.444
FEV1 (L) 3.37 iii.73 3.86 3.93 12.044 <0.001*
MVV(L) 125.47 134.26 135.54 143.95 2.834 0.039*

*Significantly different earlier and afterwards practice at different intensities (p < 0.05). FVC: forced expiratory volume. FEV1: forced expiratory book in one 2d. MVV: maximum voluntary ventilation.

Tabular array half dozen shows that the post-exercise FEV1 improvements were positively and significantly associated with MVV improvement. Nevertheless, pre-practice improvements in FVC are not associated with MVV comeback.

Table 6: Associations of MVV changes with FVC and FEV1 improvements before and after exercise

Pre
FVC FEV1
MVV R 0.140 0.038
P-Value 0.239 0.751
Post
FVC FEV1
MVV R 0.104 -0.307
P-Value 0.384 0.009**

**Pregnant at p < 0.01.

Word

Many studies have recommended treadmill aerobic do as a way to maintain or improve pulmonary role.11-12

A spirometer is an important instrument in the assessment of the lung functions. FVC, FEV1, MVV and ratio of FEV1/FVC are indicators of stiff respiratory office that deteriorate due to a sedentary lifestyle.

Prolonged aerobic exercises are idea to better aerobic chapters and to take a favorable effect on lung part. Thus, the principal aim of this study was to investigate the effect of such aerobic exercise for three weeks, specifically continuous treadmill running, on lung office (FVC, FEV1, ratio of FEV1/FVC, and MVV) in inactive yet salubrious male individuals.

Therefore, in this report, nosotros investigated the effect of 3 weeks of continuous treadmill running on FVC, FEV1, FEV1/FVC, and MVV values for 72 inactive nonetheless healthy male individuals.

FEV1 and MVV significantly improved after high-intensity aerobic exercise. In contrast, there were insignificant improvements in FVC. The comeback in FEV1 means that loftier-intensity aerobic exercise improves air flow in the respiratory tract. This finding is consistent with other studies, which postulated that FEV1 comeback is mainly acquired because the lungs expand during high-intensity aerobic do, resulting in a larger volume of air introduced into the airways and a widening of the respiratory tract.13

MVV is the measure of respiratory muscle operation. Positive relation of MVV improvement with FEV1 improvements showed that the respiratory muscle performance enhancement due to aerobic exercise can meliorate lung part. This is consistent with a previous study by Miyahara et al., in which MVV improved significantly in 18 COPD patients following a iii-week cycle ergo-meter exercise preparation program. Similarly, MVV improved significantly in 40 COPD patients subsequently a nine-week program of aerobic and upper-body practice,xivand in asthmatic subjects after a 36-session aerobic exercise program.15

Improvement in MVV later on exercise grooming could be due to increased development of respiratory musculature incidental to physical training,16 or to decreased release of inflammatory mediators in patients with bronchial asthma.17 However, if the mechanism is an increase in respiratory musculus strength production, this may explain why MVV improved significantly in the present study while FVC showed no significant increase. The increase in MVV with no improvement in FVC suggests a training issue on the respiratory muscles without an improvement in big or pocket-sized airways, as MVV is less affected by the state of airways than other parameters.

Moreover, the improvement in MVV could reflect subtle changes in lung part or airway reactivity not detected past the FVC test. In addition, higher exercise intensity or longer duration may exist needed to affect other lung function parameters similar MVV.18

What supports this idea in our report that we recruited good for you inactive subjects who values of pre FVC, FEV1 and MVV values were lower compared to predicted values results of respiratory musculus weakness due to sedentary lifestyle. This finding is consistent with Simões et al.xix who constitute that respiratory muscle strength was significantly lower in individuals with sedentary lifestyles. Thus, such subjects have needed greater preparation intensity or longer exercise duration to affect their pulmonary systems and get more significant results. Also, comeback in MVV could be due to improvement in the compliance of the lung-thorax organization later exercise training that mainly affects MVV.twenty

Many studies have shown that FVC is significantly improved subsequently loftier-intensity aerobic exercise.21-22This means that the vital capacity as well increased. It has been suggested that high-intensity aerobic exercise would increase VO2 max and activated inactive alveoli. Moreover, repeated stimulation of inspiration and expiration would increase alveolar compliance. As a effect, FVC would increase. In addition, many studies have investigated the effect of practise on FEV1/FVC and suggested that the enhancement of respiratory muscles and torso muscles and the improvement of rib cage movement had a positive effect.23-24-25

In one study, very young competitive female person swimmers were institute to take an increase in their vital capacity and total lung capacity during one year of grooming, suggesting that larger lung volumes in swimmers may be due to training. Although the mechanism by which physical inactivity might influence FVC and FEV1 is unclear, the relationship between muscular force and FVC and FEV1 is established.26

In this written report, FEV1/FVC seemed to increase significantly after practice. This result suggests that the practise used in our study was not a muscle-strengthening or rib-cage-expanding exercise, but one direct stimulating alveoli with high-intensity aerobic practice. This may explain the meaning improvements in MVV and FEV1 but non FVC.

Notwithstanding, the results of pulmonary functions in our written report cannot be compared directly with previous enquiry mainly due to the unlike method and sample size used, as well as differences in the investigated subjects' age and sex. Thus, more inquiry is needed to investigate and confirm this study's findings.

Decision

This study examines whether high-intensity aerobic exercise on a treadmill is effective in improving pulmonary function among 72 good for you inactive male person individuals. A significant improvement after practice was observed in FVC, FEV1, MVV, and FEV1/FVC. The results demonstrate that loftier-intensity aerobic exercise on the treadmill has a positive effect on the pulmonary function of inactive healthy subjects.

In conclusion, Aerobic exercise preparation should be included in plans to decrease sedentary behavior, amend aerobic chapters, and improve or at least maintain lung function in sedentary subjects. Our information suggest that a much longer do intervention or more exercise intensity may be needed to significantly improve lung role in inactive subjects.

References

  1. Courteix D, Obert P, Lecoq A.M, Guenon P, Koch G.  Result of intensive swimming preparation on lung volumes, airway resistance and on the maximal expiratory period-volume relationship in prepubertal girls. Eur J Appl Physiol Occup Physiol. 1997;76(iii):264-9.
    CrossRef
  2. Chanavirut R, Khaidjapho Chiliad, Jaree P, Pongnaratorn P.  Yoga exercise increases chest wall expansion and lung volumes in young healthy Thais. Thai Journal of Physiological Sciences. 2006;nineteen(1):1-7.
  3. Radovanovic D, Aleksandrovic G, Stojiljkovic N.D.J, Ignjatovic A, Popovic T, Marinkovic Chiliad.  Influence of concrete preparation on cardiorespiratory endurance in preadolescent age. Acta Medica Medianae. 2009;48:37-40.
  4. Garcia-Aymerich J, Lange P, Benet M, Schnohr P, Antó J.One thousand.  Regular physical activity modifies smoking-related lung part pass up and reduces risk of chronic obstructive pulmonary illness: a population-based cohort study. Am J Respir Crit Intendance Med. 2007;175(five):458-63.
    CrossRef
  5. Chang Y.F, Yang Y.H, Chen C.C, Chiang B.50.  Tai Chi Chuan training improves the pulmonary function of asthmatic children. J Microbiol Immunol Infect. 2008;41(1):88-95.
  6. Khalili M.A, Elkins Grand.R.  Aerobic do improves lung function in children with intellectual disability: a randomised trial. Aust J Physiother. 2009;55(3):171-v.
    CrossRef
  7. Lee Y.R, Yu S.J. The consequence of trip the light fantastic therapy on pulmonary and cognitive function in the elderly. J Korean Acad Nurs. 1999;29:1273–83.
    CrossRef
  8. Kim M.J, Lee J.One thousand, Jung D.Yard.  The modify of body composition, physical fitness, and capacity of the lungs co-ordinate to gateball experience in old persons. Korea J Sports Sci. 2007;16:417–26.
  9. Kang S.W, Lee S.N, Seo C.J.  The furnishings of 12 weeks core exercise on pulmonary office in elderly women. Korea J Sports Sci. 2015;24:1423-31.
  10. Cicek Chiliad, Gullu A, Gullu Eastward, Yamaner F.  The effect of aerobic and core exercises on forced vital capacity. Physical culture and sport. Turkey. 2018.
  11. Azad A, Gharakhanlou R, Niknam A, Ghanbari A.  Effects of aerobic practise on lung function in overweight and obese students. National Research Establish of Tuberculosis and Lung Disease. Iran. 2011;x(3):24-31.
  12. Chan L, Chin 50.Thou, Kennedy M, Woolstenhulme J.G, Nathan South.D, Weinstein A.A, Connors Thou, Weir N.A, Drinkard B, Lamberti J, Keyser R.E.  Benefits of intensive treadmill exercise training on cardiorespiratory function and quality of life in patients with pulmonary hypertension. Chest. 2013;143:333-43.
    CrossRef
  13. Kang, D.H: Physiology. 5th ed. Shinkwang Publication Company. 1988.
  14. Miyahara N, Eda R, Takeyama H, Kunichika N, Moriyama One thousand, Aoe 1000, Kohara H, Chikamori 1000, Maeda T, Harada, M. Effects of short-term pulmonary rehabilitation on exercise capacity and quality of life in patients with COPD. Acta Med Okayama. 2000;54(4):179-84.
  15. Haas F, Pasierski South, Levine Northward.  Effect of aerobic training on forced expiratory airflow in exercising asthmatic humans. J Appl Physiol. 1987;63:1230-5.
    CrossRef
  16. Neder, J, Andreoni S, Lerario M, Nery L. Reference values for lung function tests: II. Maximal respiratory pressures and voluntary ventilation. Braz J Med Biol Res. 1999;32(6):719-27.
    CrossRef
  17. Dassios T, Katelari A, Doudounakis S, Dimitriou Chiliad.  Aerobic exercise and respiratory musculus strength in patients with cystic fibrosis. Respiratory Medicine. 2013;107:684-xc.
    CrossRef
  18. Gimenez Grand, Servera East, Vergara P, Bach J, Polu J.  Endurance grooming in patients with chronic obstructive pulmonary illness: A comparison of high versus moderate intensity. Arch Phys Med Rehabil. 2000;81:102-9.
    CrossRef
  19. Simões R.P, Deus A.P Auad Thousand.A, Dionísio J, Mazzonetto M, Borghi-Silva A. Maximal respiratory pressure in salubrious 20 to 89 year-old sedentary individuals of fundamental São Paulo Country. Rev Bras Fisioter. 2010; 14(1):60- vii.
    CrossRef
  20. Neder J, Andreoni S, Lerario Grand, Nery L.  Reference values for lung role tests: II. Maximal respiratory pressures and voluntary ventilation. Braz J Med Biol Res. 1999;32(six):719-27.
    CrossRef
  21. Farrell P.A.  Maximal expiratory flow-volume relationships before and subsequently eight weeks of endurance training. J Sports Med Phys Fitness. 1981;21(2):145-9.
  22. Lee J.Y, Jung J.H, Chung E.J. The effect of feedback animate exercise and treadmill exercise on chest length and pulmonary function of the middle-anile. J Spec Educ Rehabil Sci. 2013;52:319-33.
  23. Park J, Han D.  Furnishings of high intensity aerobic exercise on treadmill on maximum-expiratory lung capacity of elderly women. J Phys Ther Sci. 2017;29(8):1454-1457.
    CrossRef
  24. Lee B, Park South, Han D.  Analysis of the influential factors of maximal-effort expiratory chapters of elderly women. J Phys Ther Sci. 2016;28:2924-2928.
    CrossRef
  25. Vocal J.W, Kim G.D.  Effects of core stability training on the pulmonary function and trunk muscle activeness in chronic stroke patients. Asia-pacific Journal of Multimedia Services convergent with Fine art. 2016;six:101-108.
    CrossRef
  26. Courteix D, Obert P, Lecoq A.1000, Guenon P, Koch G. Outcome of intensive swimming training on lung volumes, airway resistance and on the maximal expiratory menstruum-volume relationship in prepubertal girls. Eur J Appl Physiol Occup Physiol. 1997;76(iii):264-9.
    CrossRef

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